Copper is an essential micro-mineral which is necessary for the maintenance of normal hemoglobin status and is also a part of many enzyme systems. Many physiological functions in mammals are dependent on the availability of copper.
Copper in blood exists in the form of copper protein complex. It also acts as an agent in preventing anaemia may be due to the ability to assist the absorption of iron and to stimulate or accelerate the synthesis of the non- protein haeme or globin part of haemoglobin present in the blood.
Copper -plays an important role in the metabolism of fatty acids and in the formation of ribonucleic acid (RNA) which does the function of coding, decoding and regulation of the genes. Copper in the body is capable of binding bacterial toxins and increases the activity of antibiotics.
Absorption and metabolism:
Typical diets provide about 1 mg of copper per day, that is about 25-40 per cent of which is absorbed. Copper is absorbed from all parts of the gastrointestinal tract including the stomach and large intestine.
The total copper content of the body is estimated at 75 to 150 mg. 40 percent of which is found in muscles. The liver with 15 per cent body copper is the major copper storage site.
Copper deficiency is rare in humans. It occurs mainly in infants resulting in psycho-motor retardation( involves a slowing-down of thought and a reduction of physical movements in an individual), hypopigmentation, anaemia, osteoporosis etc.
Some of the rich sources of copper are seafoods like oysters, crabs and lobster, meat sources followed by nuts and dried legumes like almonds, sesame, sunflower and soyabean contain12-37 microgram/gm. Fruits and vegetables have only low content of copper about 0.3 microgram/gm. In seeds, and other grains, most of the bran and germ. Refining of flour removes most of the copper.